Historical, retrospective cohort study evaluation (n=666) comparing the effectiveness of chitosan covered (CELOX PPH) Gauze with balloon tamponade or medical therapy in patients with PPH

Does the use of CELOX™ PPH for postpartum haemorrhage reduce the need for surgical therapy including hysterectomy? A databased historical cohort study.

Biele C, Radtke L, Kaufner L, Hinkson L, Braun T, Henrich W, Dückelmann AM. J Perinat Med. 2022; 50(8):1078-1086.

Retrospective cohort study (n=666)

  • Assessment of the effectiveness of CELOX™ PPH in comparison with balloon tamponade, and medical therapy only
  • Groups were compared in terms of therapy success, side-effects, and the primary outcome was the need for surgical measures (e.g., hysterectomy)
  • No significant differences in the need for surgical therapy between groups.
  • CELOX™ PPH group had significantly fewer hysterectomies compared to the balloon tamponade group.
  • Following the introduction of CELOX™ PPH, the incidence of PPH-related hysterectomies was significantly reduced by 77.8%.
  • No adverse events related to CELOX™ PPH
  • CELOX™ PPH is easy to use and cost-effective compared to alternative devices.
Fast acting Safe and clinically effective Versatile and Easy to use
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